There is a long history of electrical stimulation to treat epileptic seizures, but none of it has been able to utilize the effective forms of modern control engineering. This situation is about to change. It is based upon the convergence of increasing understanding of the mechanisms of seizures, computational models that reflect such mechanisms, and the advances in model based control that now permit us to incorporate the features in neuronal models that previously prevented such applications. Such techniques are not restricted to epileptic seizures, but are also applicable to the control of cognitive rhythms, and the modulation of motor system dysfunction as in Parkinson¹s disease. 

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