CIMIT Funded Projects 2010

CIMIT Community

CIMIT Innovation Grants

Accepting Pre-proposals Jan. 1 - Feb. 15, 2010

CIMIT Innovation Grants support early stage, collaborative research projects for improving patient care, with emphasis on devices, procedures, diagnosis, and clinical systems. CIMIT awards grants to principal investigators on faculty at the CIMIT Consortium institutions. Projects may include team members from other academic institutions and collaborators from industry. Awards will be for up to $70,000, direct cost.

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CIMIT Projects

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Fiscal Year	Principal Investigator	Project Title	Institution	Program Area
2010	Bigio, Irving, PhD	Validation of colon cancer screening by optical sensing of field effect in rectal mucosa	BU	Optical Diagnostics
2010	Edelman, Elazer, MD, PhD	Tissue engineering therapies for inhalation injury	MIT, BWH	Inhalation Technology
2010	Elman, Igor, MD	Novel predictors of pharmaco-therapeutic outcomes using functional reciprocity between heightened stress reactivity and emotional numbing in PTSD	McLean Hospital, HMS	PTSD
2010	McLaughlin, Bryan, PhD	An implantable, wireless electrode derivation for chronic EEG recording in epilepsy	Draper Labs	Neurotechnology
2010	Neumann, Paul, PhD	Eye trauma simulator	MGH	Simulation
2010	Otterbein, Leo, PhD	Inhalation of medicinal gases targeting new pathways for the treatment of sepsis	BIDMC	Biodetection & Sepsis Control
2010	Vakoc, Benjamin, PhD	An image-guided laser therapy catheter for Barrett’s esophagus	MGH	Optical Diagnostics
2010	Weinstock, Peter, PhD, MD	Development of an integrated child circulatory system simulator to enhance patient safety via procedural skills and team training in pediatrics	CHB	Simulation
2010	Yoo, Seung-Schik, PhD, MBA	Direct functional brain mapping using image-guided focused ultrasound	BWH	Image Guided Therapy
2010	Yun, Seok, PhD	Dynamic cross sectional and functional imaging of vocal folds (4D laryngoscopy)	MGH	Optical Diagnostics
2010	Weiner, Debra, MD, PhD	Handheld simulation procedure training device	CHB	Clinical Systems Innovation
2010	Dierks, Meghan, MD	Reshaping systems, processes and controls to optimize outcomes in sepsis	BIDMC	Clinical Systems Innovation
2010	Bonato, Paolo, PhD	Combining galvanic vestibular stimulation and motor training in traumatic brain injury survivors with neglect	Spaulding Rehab	TBI
2010	Fregni, Felipe, MD, PhD, MPH	Closed loop, detect-and-treat systems for epilepsy	BIDMC	Neurotechnology
2010	Golby, Alexandra, MD	A hybrid optic-electromagnetic surgical tool tip tracking system for neurosurgery	BWH	Image Guided Therapy
2010	Kheir, John, MD	Use of topical oxygen mirobubbles to enhance wound healing	CHB	Trauma & Casualty Care
2010	Mazumder, Malay, PhD	Electrostatic dry powder inhaler for constant dose respiratory drug delivery	BU	Inhalation Technology
2010	Poznansky, Mark, MD, PhD	A cutaneous laser system for augmenting the immunogenicity of HIV vaccines	MGH	New Initiatives
2010	Redmond, Robert, PhD	A photo-activated nanofiber graft material for enhanced tendon repair	MGH	Biomaterials & Tissue Engineering
2010	Spector, Jonathan, MD, MPH	Resuscitation technology for saving newborn lives	MGH	Global Health Initiative
2010	Tullius, Stefan, MD, PhD	A system to measure continuous flow and perfusion to ensure successful kidney transplantation	BWH	Image Guided Therapy
2010 - 2009	Colson, Yolonda, MD, PhD	Expansile Nanoparticles for Tumor-Targeted Drug Delivery to Prevent Lymph Node Metastases in Breast Cancer	BWH, BU	Biomaterials & Tissue Engineering
2010 - 2009	Demirci, Utkan, PhD	Disposable Filter-Based Microfluidic Chip for HIV CD4 Monitoring in Resource-Limited Settings	BWH	New Initiatives
2010 - 2009	Ingber, Donald, MD, PhD	Microfluidic Blood Cleansing Device for Sepsis Therapy	CHB, Draper	Biodetection & Sepsis Control
2010 - 2008	Rattner, David, MD	Strategic Project on Natural Orifice Translumenal Endoscopic Surgery	MGH	Minimally Invasive Surgery
2010 - 2009	Toner, Mehmet, PhD	A Label-Free Viral Detection Microchip for Point-of-Care Applications	MGH, MIT	Biodetection & Sepsis Control
2010 - 2009	Levine, Robert A., MD	Operating on the Heart from Within -- A Minimally Invasive Approach to Mitral Valve Disease	MGH, MIT	Cardiovascular Disease
2009	Bergethon, Peter, PhD	Multi-Optode Probe for Evaluation of Diabetic Neuropathy	BU, Tufts	Neurotechnology
2009	Cash, Sydney, MD, PhD	Microelectrode Recordings and Advanced Algorithms for Seizure Prediction	MGH, MIT, Brown, BWH, CHB	Neurotechnology
2009	Hamblin, Michael, PhD	Transcranial NIR Light for Traumatic Brain Injury	MGH, CHB	Trauma & Casualty Care
2009	Hata, Nobuhiko, PhD	Swimming Capsule Endoscope	BWH, Swiss Federal Institute of Technology	Image Guided Therapy
2009	Hung, Judy, MD, PhD	Polymer Injection for Treatment of Ischemic Mitral Regurgitation	MGH	Cardiovascular Disease
2009	Klapperich, Catherine, PhD	A Microfluidic System for Monitoring Sepsis at the Point of Care	BU, BWH	Biodetection & Sepsis Control
2009	Lin, Charles, PhD	Label-free Detection and Quantification of Circulating Leukocytes by in vivo Flow Cytometry	MGH, BIDMC	Optical Diagnostics
2009	Sheridan, Rob, MD	Magnetic Endotracheal Tube Imaging Device	MGH, MIT	New Initiatives
2009	Tearney, Guillermo, MD, PhD	Integrated OFDI-Fluorescence Catheter for Imaging of Atherosclerosis	MGH	Cardiovascular Disease
2009	Teng, YD, MD, PhD	Antioxidant and Injectable Biodegradable Polymers to Promote Functional Recovery from Traumatic Spinal Cord Injury (SCI)	BWH, MIT	Trauma & Casualty Care
2009	Yun, Seok, PhD	Novel Ocular Biomechanical Analysis	MGH, MIT, MEEI	Optical Diagnostics
2009	Denis, Gerald, PhD	Ultrasound-directed Delivery of Cancer Chemotherapeutic Drugs	BU, BMC	Image Guided Therapy
2009	Fennessy, Fiona, PhD	Computer-assisted Tumor Blood Vessel Tortuosity Analysis at 3T as a Method of Assessing Ablative Therapy Response	BWH, UNC	Image Guided Therapy
2009	Fregni, Felipe, MD, PhD	The Effect of Transcranial Direct Current Stimulation Combined with Arm Training Using Glove-ArMEO Robotic Device on Motor Recovery in Traumatic Brain Injury Survivors	BIDMC, Spaulding	Image Guided Therapy
2009	Kaplan, David, PhD	A Rapid Disposable Device for Early Detection of Sepsis	Tufts, Draper, BIDMC	Biomaterials & Tissue Engineering
2009	Lim, Chun, MD, PhD	Augmented Reality Glasses for the Treatment of Visuospatial Neglect	BIDMC, Draper	Neurotechnology
2009	Manstein, Dieter, MD	Non-Invasive Measurement of Intraepidermal Nerve Density	MGH	Optical Diagnostics
2009	Pascual-Leone, Alvaro, MD, PhD	Near-Infrared Photobiostimulation as a Means of Neuromodulation in Stroke	BIDMC, CHB	Neurotechnology
2009	Pelton, Stephen, MD	Development of Safe and Effective Novel Transtympanic Membrane Strategy for Treatment of Acute Bacterial Otitis Media	BMC, BUMC, CHB, MIT	New Initiatives
2009	Schlaug, Gottfried, MD, PhD	TDCS - Stroke Recovery	BIDMC, Penn State	Neurotechnology
2009	Sundback, Cathryn, ScD	Poly(glycerol sebacatge) Film as Barrier to Formation of Viscero-Parietal Peritoneal Adhesions	MGH	Biomaterials & Tissue Engineering
2009	Dixon, Ronald, MD	Healthcare 360: A Technology-Enabled Model for General Medical Care	MGH	Clinical Systems Innovation
2009	Newbower, Ronald, PhD	Handwashing Compliance Reminder and Documentation	MGH	Clinical Systems Innovation
2008	Barbieri, Riccardo, MD	A Computational Tool Based on Heart Beat Dynamics to Predict Apnea Episodes in Premature Infants under Vibro-tactile Stimulation	MGH, UMASS	Neurotechnology
2008	Bhattacharyya, Timothy, MD	FractureFree Stem Inserter for Total Hip Arthroplasty: Improving Patient Safety by Enhancing Surgeon Feedback	MGH, MIT	Biomaterials & Tissue Engineering
2008	Bonato, Paolo, PhD	Enhancing Parkinson's Control Therapy by Stimulation of the Subthalamic Nucleus via Measures of Motor Response	Spaulding, BIDMC	Neurotechnology
2008	Butte, Manish, PhD	Development of a Prototype Microfludic Detector Enabling CD4 T Cell Counting in HIV/AIDS	Harvard	Global Health Initiative
2008	Colson, Yolonda, MD	Validation of Imaging System for Near-Infrared Image Guided Sentinel Lymph Node Dissection in Lung Cancer	BWH, BIDMC	Image Guided Therapy
2008	Demirci, Utkan, PhD	Interdigitated Electrodes for Disposable HIV Diagnostics	MIT, Harvard	New Initiatives
2008	Dzik, Walter H., MD	RFID for prevention of bedside errors	MGH	Clinical Systems Innovation
2008	Fregni, Felipe, MD, PhD	Anticonvulsive and Antiepileptic Properties of Transcranial Direct Current Stimulation (tDCS) in an Animal Seizure Model	BIDMC, CHB	Neurotechnology
2008	Goldman, Julian M., MD	Medical Device Mobile Plug-and-Play Platform (MD MP3) for Medication Safety	MGH	Clinical Systems Innovation
2008	Hata, Nobuhiko, PhD	Swimming Capsule Endoscope for Diagnosis and Treatment of Small Intestine	BWH	Image Guided Therapy
2008	Horenstein, Mark, PhD	Transdermal Injection of Nano Particles via Electrospray and Pulsed-Field Assist	BU	Biomaterials & Tissue Engineering
2008	Insoft, Robert, MD	Improving the Care of Neonates During Inter-hospital Transport	BWH, MIT, Anna Jacques Hospital	Clinical Systems Innovation
2008	Judge, David, MD	Designing the Ambulatory Practice of the Future Systems Integration Hub	MGH	Clinical Systems Innovation
2008	Lee, Richard T., MD	A Novel Bio-Instructive Surface for Generating Osteoblastic Cells in the OR	BWH, MIT	Biomaterials & Tissue Engineering
2008	McDannold, Nathan, PhD	Herceptin Delivery to Breast Cancer Metastases in the Central Nervous System via Focused Ultrasound-Induced Blood-Brain Barrier Disruption	BWH	Minimally invasive Surgery
2008	Mertz, Jerome, PhD	Hybrid-Illumination Fluorescence Macroscopy with Out-of-Focus Blur Rejection	BU, BIDMC	Optical Diagnostics
2008	Nakajima, Nobuyuki, MD	Real-time electromagnetic navigation for flexible-neuroendoscopy	BWH	Neurotechnology
2008	Klapperich, Catherine, MD	Integrated Microfluidic Platform for Detection and Diagnosis of Avian Influenza	BU, BMC	Global Health Initiative
2008	Golby, Alexandra, MD	Intracranial Electrophysiology System for the Intraoperative MRI	BWH, MGH	Neurotechnology
2008	Verrier, Richard L., MD	Development and Clinical Database Testing of Automated ECG Heterogeneity Analyzer for Real-Time Assessment of Risk for Lethal Arrhythmia	BIDMC	Cardiovascular Disease
2008	Madsen, Joseph R., MD	A Device for Quantifi cation of the Ballistocardiogram (BCG) as a Non-Invasive Measure of Intracranial Dynamics	CHB, MGH	Neurotechnology
2008	Masiakos, Peter T., MD	Development of an Endoscopic Fiberoptic Device and Biodegradable Scaffolds for Minimally Invasive Closure of Tracheoesophageal Fistulas	MGH, MEEI	Minimally invasive Surgery
2008	Neumann, Paul F., MD	Integrating Intelligent Tutoring into Simulation	MGH	Simulation
2008	Ottensmeyer, Mark P., PhD	Multi-Axial Multi-Instrument Tracking System for Endovascular Interventional Radiology Simulator	MGH	Simulation
2008	Pang, Trudy, MD	Initial Clinical Implementation of a Novel, Non-Invasive, Patient-Specific Electrographic Seizure Detection System with Two Outputs: An Audible Alarm and Energized Electromagnets for Activation of Vagus Nerve Stimulation	MIT, BIDMC	Neurotechnology
2008	Thomas, Robert Joseph, MD	Cervical Direct Current Carotid Body Stimulation: Preliminary evaluation of a novel method to modulate carotid chemoreflex function for treatment of central and complex sleep apnea	BIDMC	Neurotechnology
2008	Winograd, Jonathan M., MD	Design of an Autonomous Brain-Body Interface in the Spinal Cord-Injured Patient	MGH, MIT	Neurotechnology
2008	Rutkove, Seward, MD	Refinement and Application of an Electrical Impedance Probe for Neuromuscular Assessment	BIDMC, MIT	Neurotechnology
2008	Ryou, Marvin, MD	Systematic Mapping of NOTES Access Sites in Human Cadavers	BWH, MGH	Minimally Invasive Surgery
2008	Ryou, Marvin, MD	Magnetic Retraction for Advanced NOTES Procedures	BWH, MGH	Minimally Invasive Surgery
2008	Colson, Yolonda, MD	Clinical Prototype for Intraoperative Aerosolized Nanoparticle Drug Delivery	BWH, BU	Biomaterials & Tissue Engineering
2008	Pien, Homer, PhD	A Multidisciplinary Approach to Improving Perfusion Imaging	MGH, Draper, BU	Image Guided Therapy
2008	Warfield, Simon, PhD	Bayesian Source Imaging of Pediatric Epilepsy	CHB	Neurotechnology
2008	Levy, Bruce D., MD	Remotely Monitored Inhaler to Predict and Prevent Asthma Attacks	BWH	Clinical Systems Innovation
2008	Larson, Dale, PhD	Development of a Rapid, Sensitive Test for Sepsis	Harvard, Draper, BWH	Biodetection & Sepsis Control
2008	Karp, Jeffrey M., PhD	Intraoperative Programmable Autologous Stem Cell Therapy	BWH, MGH	Biomaterials & Tissue Engineering
2008	Wolfberg, Adam, MD, MPH	The Safe Fetus Project: Develop a new non-invasive monitor of fetal health	CHB, MIT	Clinical Systems Innovation
2007	Ingber, Donald, MD, PhD	Nanomagnetic-Microfluidic Separator for Sepsis Control	CHB	Biodetection & Sepsis Control
2007	Murray, Martha, MD	Arthroscopic Joint Repair System	CHB	Biomaterials & Tissue Engineering
2007	Yaroslavsky, Anna, PhD	Wide-Field, High-Resolution Imaging for the Detection of Nonmelanoma Skin Cancers	MGH	Image Guided Therapy
2007	Colson, Yolonda, MD	Pre-Clinical Study of Drug Delivery Microsphere Incorporation at Surgical Resection Margin	BWH	Minimally Invasive Surgery
2007	del Nido, Pedro, MD	Cardio-Port for Minimally Invasive Intracardiac Beating Heart Surgery	CHB	Minimally Invasive Surgery
2007	Mayer, John, MD	Tissue Engineering of Pulmonary Valves for Application in Congenital Heart Disease	CHB	Tissue Engineering, Cardiovascular Disease
2007	Brown, Robert, MD, PhD	Nanoparticles for MRI-based Imaging of Axonal Transport in ALS	MGH	Image Guided Therapy
2007	Masiakos, Peter, MD	Development of an Endoscopic Fiberoptic Device and Biodegradable Scaffolds for Minimally Invasive Closure of Tracheoesophageal Fistulas	MGH	Minimally Invasive Surgery
2007	Rutkove, Seward, MD	A Handheld Electrical Impedance Probe for the Assessment of Neuromuscular Disease	BIDMC	Neurotechnology
2007	Bonato, Paolo, PhD	Development of a Markerless System for Clinical Analysis of Gait Abnormalities	Spaulding	Clinical Systems Innovation
2007	Bonventre, Joseph, MD, PhD	Characterization and Validation of "RenAlert": A Silicon Nanowire Device for Early Diagnosis of Acute Kidney Injury	BWH	Clinical Systems Innovation
2007	Washko, George, MD	Quantitative Analysis of Airways and Airspace Disease Visualized on Computer Tomographic Imaging in Subjects with COPD	BWH	Image Guided Therapy
2007	Yun, Andy, PhD	Brillouin Microscopy for Tissue Biomechanics	MGH	Tissue Engineering
2007	Edelman, Elazer, MD, PhD	High Throughput Flow System for the Generation of Thrombotic Fingerprints	MIT	Clinical Systems Innovation
2007	Kacher, Daniel, MS	Radiofrequency Identification for Tracking of Surgical Instruments in the Intra-Operative Environment	BWH	Clinical Systems Innovation
2007	Samset, Eigil, PhD	MRI-Guided Cardiac Ablation Using EM Trackable Catheters and Real-Time MRI Scanner Control	BWH	Image Guided Therapy, Cardiovascular Disease
2007	Thompson, Christopher, MD	Sterile Access Conduit	BWH	Minimally Invasive Surgery
2007	de Boer, Johannes, PhD	Spectral-Domain Optical Coherence Reflectometry for Highly Sensitive and Selective Detection of Biological and Chemical Species	MGH	Image Guided Therapy
2007	Gupta, Rajiv, MD	Dynamic Imaging and Neuro Interventions Using a High-Resolution Flat-Panel Volume CT: Feasibility Demonstration	MGH	Image Guided Therapy, Neurotechnology
2007	Khademhosseini, Ali, PhD	Microencapsulation of Cells within Shape-Controlled Microgels as Building Blocks for Tissue-Engineered Organs	MIT	Tissue Engineering
2007	Karl, William, PhD	Cardiac MDCT Artifact Reduction	BU	Cardiovascular Disease
2007	Bernstein, Jonathan, PhD	Micromirror Based 3D Endoscopy	Draper	Minimally Invasive Surgery
2007	Whitesides, George, MD	Development of a Prototype Microfluidic Detector Enabling CD4 T Cell Counting in HIV/AIDS	Harvard	Global Health Initiative
2007	Yelin, Dvir, PhD	Comprehensive Volumetric Confocal Microscopy via Spectral Encoding	MGH	Image Guided Therapy
2007	Paltiel, Harriet, MD	Three Dimensional Ultrasound Imaging of Testicular Perfusion	CHB	Image Guided Therapy
2007	Laham, Roger	Percutaneous Biopsy and Implantation Catheter Device for Autologous Myocardial Tissue Transplantation	BIDMC	Cardiovascular Disease
2007	Merabet, Lotfi, OD, PhD	A Multi-Modal Sensory Rehabilitative Strategy for the Augmentation of Functional Vision	BIDMC	Clinical Systems Innovation
2007	Pascual-Leone, Alvaro, MD	Modularized, Portable, Transcranial Magnetic Stimulation (TMS) Device	BIDMC	Neurotechnology
2007	Grinstaff, Mark, PhD	Preparation and Evaluation of Functional Nanospheres	BU	Biomaterials & Tissue Engineering
2007	Chen, Frederick, MD	Quantitative Cardiac Restraint: Therapy for Ischemic Mitral Regurgitation	BWH	Cardiovascular Disease
2007	Thompson, Christopher, MD	Endoscopic Transcolonic Cholecystectomy in a Porcine Model: A Survival Study	BWH	Minimally Invasive Surgery
2007	Jensen, Klavs, PhD	High-Throughput Quantitative Microinjection into Individual Cells	MIT	Biomaterials & Tissue Engineering
2007	Ellsmere, James, MD	MR-Compatible Endoscopy	BIDMC	Minimally Invasive Surgery
2007	Pierce, Eric, MD	Total Intravenous Anesthesia Machine of the Future (TIVA Solutions): The Missing Element for Highly Portable Anesthesia	MGH	Clinical Systems Innovation
2007	Bergethon, Peter, MD	A Device for Imaging the Neuroanatomy and Transport Function of Peripheral Nerves	BU	Neurotechnology
2007	de Boer, Johannes, PhD	Optical Detection of Neural Activity for Neurosurgical Repair	MGH	Image Guided Therapy, Neurotechnology
2007	Vosburgh, Kirby, PhD	Novel Image Registered Procedures	BWH, MGH	Image Guided Therapy
2007	Zeitels, Steven, MD	Photoangiolysis in the Treatment of Oral Mucosal Squamous Cell Carcinoma in the Hamster Cheek Pouch Model	MGH	Image Guided Therapy
2007	Guttag, John, PhD	Finding Medically Relevant Patterns in Lengthy Streams of Physiological Data	MIT	Clinical Systems Innovation
2007	Ducko, Christopher, MD	Implementation of a Phrenic Nerve Pacemaker Program	BWH	Neurotechnology
2007	Tavakkolizadeh, Ali	Hybrid Training in Translumenal Surgery	BWH	Minimally Invasive Surgery
2007	Berger, David, MD	The Operating Room POD Program	MGH	Clinical Systems Innovation
2007	Dierks, Meghan, MD	Risk Assessment Modeling Tools for Clinical System Redesign and New Technology Adoption	BIDMC	Clinical Systems Innovation
2007	George, Ed, MD, PhD	Disaster Response: A National Priority -- Addressing Medical Device Surge Capacity	MGH	Trauma & Casualty Care
2007	Goldman, Julian, MD	Medical Device Plug and Play Standardization	MGH	Clinical Systems Innovation
2007	Kourembanas, Stella, MD	NICU of the Future	CHB	Clinical Systems Innovation
2007	Sandberg, Warren, MD	Extension of the CIMIT OR of the Future "Catalystic Site" to New Surgical Workflows in a Major Academic Center	MGH	Clinical Systems Innovation
2007	Schomer, Donald	Design and Development of a Prototypic EEG+ Monitor for the ICU	BIDMC	Trauma & Casualty Care
2007	Anderson, Philip, MD	Emergency Department of the Future: Prototyping the "Smart" Wearable Emergency Triage Monitor	BIDMC	Trauma & Casualty Care
2007	DiMaio, Simon, PhD	Assurance of Safety and Efficacy in Multi-Modality Image-Guided Neurosurgery	BWH	Image Guided Therapy, Neurotechnology
2007	Ditomassi, Marianne	Application of Emerging Technology in Retention of an Aging Nursing Workforce	MGH	Clinical Systems Innovation
2007	Gray, James, MD	Integrating and Managing Device Information in NICU of the Future: Improving on the Cost-Efectiveness of NICU Staffing	BIDMC	Clinical Systems Innovation
2007	Gray, James, MD	Device Technologies for the NICU of the Future	BIDMC	Clinical Systems Innovation
2007	Judge, David, MD	Ambulatory Practice of the Future: Systems Integration at the Heart of the Matter	MGH	Clinical Systems Innovation
2007	Kourembanas, Stella, MD	Working Group for NICU Technology Development	CHB	Clinical Systems Innovation
2007	Sandberg, Warren, MD	Automatic Detection and Machine Assisted Correction of Equipment Errors During Anesthesia	MGH	Clinical Systems Innovation
2006	Asada, Harry, PhD	Blood Pressure Measurement by Touch: A Glove or Wand Probe for Use in Hazardous Environments	MIT	Trauma & Casualty Care
2006	Baim, Don, MD	Percutaneous Valve Working Group	BWH	Minimally Invasive Surgery
2006	Bernstein, Jonathan, PhD	Micromirror Based 3D Endoscopy	Draper	Minimally Invasive Surgery
2006	Bonato, Paolo, MD	Wearable Wireless Sensor Network to Monitor Recovery in Post-Stroke Patients	Spaulding	Clinical Systems Innovation
2006	Borenstein, Jeffrey, PhD	3D Biomaterial Structures for Endothelial Cell Tissue Engineering Applications	Draper	Tissue Engineering
2006	Brugge, William, MD	Endoscopic Cord Biopsy Needle with Flexural Members	MGH	Minimally Invasive Surgery
2006	Bueno, Raphael, MD	Development of the ORF Concept at BWH	BWH	Clinical Systems Innovation
2006	Cohen, Richard, PhD	Continuous Cardiac Output Monitoring for Combat Casualty Care	MIT	Trauma & Casualty Care
2006	Colson, Yolonda, MD	Local Incorporation of Anti-Neoplastic Agents into Surgical Resection Margins Using a Minimally Invasive Delivery System	BWH	Minimally Invasive Surgery
2006	Cotin, Stephane, PhD	Computational Tools for Interventional Radiology -- Application to Stroke Diagnosis	MGH	Neurotechnology
2006	Davidson, Michael, MD	Fellowship in Integrative Cardiac Intervention	BWH	Cardiovascular Disease, Young Clinician Award
2006	Ellis, Randy, MD	Multimodality Image Guided Therapy	BWH	Image Guided Therapy
2006	Ellis, Randy, MD	Technology for Advanced CT-Guided Biopsy	BWH	Image Guided Therapy
2006	Evans, Christopher H., PhD	Device for Harvesting and Transfecting Fat MSC for Use in Bone Repair	BWH	Biomaterials & Tissue Engineering
2006	Fauza, Dario, MD	Optical Enhancement in Videofetoscopy	CHB	Image Guided Therapy
2006	Frangioni, John, MD, PhD	Artificial Protons: Micro-Resonant Devices for High Sensitivity Three-Dimensional Localization in Medicine	BIDMC	Image Guided Therapy
2006	Goldman, Julian, MD	Medical Device Plug-And-Play Interoperability Standardization Program Development	MGH	Clinical Systems Innovation
2006	Gupta, Rajiv, MD, PhD	A Needle Guidance System for Percutaneous, Image-Guided Biopsies	MGH	Image Guided Therapy
2006	Jiang, Yandong, MD	A Novel Negative Pressure Ventilation System	MGH	Clinical Systems Innovation
2006	Judge, David, MD	Ambulatory Practice of the Future	MGH	Clinical Systems Innovation
2006	Kohane, Daniel, MD, PhD	Chemoembolization for Heptocellular Carcinoma	MGH	New Initiatives
2006	Kvedar, Joseph, MD	Connected Health Initiative: Creating a Roadmap for the Management of Hypertension and Diabetes Within a Virtual Practice at MGH	MGH	Clinical Systems Innovation
2006	Lee, Richard, MD	Injectable Nanofiber Delivery of siRNA to Myocardium	BWH	Cardiovascular Disease
2006	Levy, Bruce, MD	Remotely Monitored Inhaler to Predict and Prevent Asthma Attack	BWH	Clinical Systems Innovation
2006	Mootha, Vamsi, MD	A Microphysiometer for Quantitative Measurements of Mitochondrial Function	MGH	New Initiatives
2006	Murray, Martha, MD	Enhanced Arthroscopic Repair of Meniscal Injuries	CHB	Minimally Invasive Surgery
2006	Shekar, Prem, MD	Planning and Development of a Hybrid Cardiovascular Operating Room	BWH	Clinical Systems Innovation, Cardiovascular Disease
2006	Tearney, Gary, MD, PhD	Optical Frequency Domain Interferometry for the Determination of Cerebral Aneurysm Rupture Risk	MGH	Image Guided Therapy
2006	Thompson, Christopher, MD David Rattner, MD	Endoscopic Surgery Working Group	BWH, MGH	Minimally Invasive Surgery
2006	Towle, Christina, PhD	A Translational Study of Photodynamic Manipulation of TGFß Signaling Pathways in Preclinical Models -- Minimally Invasive to Counteract Cartilage Degeneration in Osteoarthritis	MGH	Minimally Invasive Surgery
2006	Tupper, Malinda, PhD	Novel Clinical Diagnostics Using Differential Mobility Spectrometry and Bioinformatics	Draper	Image Guided Therapy
2006	Velmahos, George, MD	Portable Insufflator Device for Reduction of Intra-Abdominal Bleeding in Field Applications	MGH	Trauma & Casualty Care
2006	Velmahos, George, MD	Tele-Linkage of Prehospital Health Care Providers with In-Hospital Trauma Team	MGH	Clinical Systems Innovation, Trauma & Casualty Care
2006	Verrier, Richard, MD	Novel Technology for Transvenous Catheter-Based Chronic Intrapericardial Therapeutics	BIDMC	Cardiovascular Disease
2006	Vosburgh, Kirby, PhD	Improved Guidance for Minimally Invasive Interventions	BWH, MGH	Minimally Invasive Surgery
2006	Vunjak-Novakovic, Gordana, PHD	Small Well Plate	MIT	New Initiatives
2006	Warfield, Simon, MD	Improved Analysis for Patient-Specific Epilepsy Surgical Planning	CHB	Neurotechnology
2006	Weiss, Anthony, MD	Hallucination Monitoring Using Near-Infrared Spectroscopy	MGH	Image Guided Therapy
2006	Westin, Carl-Fredrick, PhD	Real-Time Control of 3D-Slicer Visualization Using Coordinates from Electrophysiological Catheter Tracking System	BWH	Image Guided Therapy
2006	Whang, Edward, MD	Localized and Sustained Polymeric Delivery of siRNA for Treatment of Pancreatic Cancer	BWH	Biomaterials & Tissue Engineering
2006	White, Jennifer, MD	A New Apparatus for the Effective Testing of Cutting-Edge Heart Valve Therapies	MGH	Cardiovascular Disease
2006	Whitesides, George, PhD	Microfluidic Device for Low-Cost Screening of Newborns for Severe Combined Immune Deficiency	Harvard	Global Health Initiative
2006	Weinmann, Maxwell, MD	Chemiluminescent Medical Devices	BWH	Image Guided Therapy
2006	Yelick, Pamela, PhD	Composite Titanium/Bioengineered Dental Tissue implants	Forsyth	Tissue Engineering
2005	Bernstein, Jonathan, PhD	Micromirror Based 3D Endoscopy	Draper	Minimally Invasive Surgery
2005	Bouma, Brett, PhD	Therapy Enabling Device: in situ, Real-Time Monitoring of Laser Ablation	MGH	Image Guided Therapy
2005	Cotin, Stephane, PhD	Hybrid Simulation System for Stroke Therapy team Training	MGH	Simulation
2005	Davis, Cristina, PhD	Bacillus Spore Identification using FAIMS and Bioinformatics Pattern Recognition	Draper	Biodetection & Sepsis Control
2005	Davis, Cristina, PhD	Novel Clinical Diagnostics using FAIMS and Bioinformatics Pattern Recognition	Draper	Biodetection & Sepsis Control
2005	du Plessis, Andre, MD	Development of a Bedside Cerebrovascular Monitor for Identifying Premature Infants at Risk for Brain Injury	CHB	Neurotechnology
2005	Ferrigno, Massimo, MD	Warming Hypothermic Patients Through the Respiratory System During Medical Evacuation	BWH	Trauma & Casualty Care
2005	Frangioni, John, MD	Improved Deep Tissue Sensitivity for Intraoperative Near-Infrared Fluorescence Imaging	BIDMC	Image Guided Therapy
2005	Georgakoudi, Irene, MD	Development of Light Scattering Based in vivo Flow Cytometry	MGH	Image Guided Therapy
2005	Gray, James, MD	Use of Radiofrequency ID to Reduce Patient Identification Errors in the Neonatal Intensive Care Unit	BIDMC	Clinical Systems Innovation
2005	Iftimia, Nicusor, MD	Endoscopic Full-Field Optical Coherence Microscopy System for Clinical Diagnosis	MGH	Image Guided Therapy
2005	Krissian, Karl, MD	Freehand Ultrasound Image Guided Laparoscopic Surgery	BWH	Image Guided Therapy, Minimally Invasive Surgery
2005	Mayer, John E., MD	Tissue Engineering of Pulmonary Valves for Congenital Heart Disease	CHB	Cardiovascular Disease, Tissue Engineering
2005	Mizuno, Shuichi, PhD	Development of an Injectable Chondrocyte/Matrix in a Semi-Permeable Pouch Manipulated Using Physical Stimuli	BWH	Biomaterials & Tissue Engineering
2005	Muratoglu, Orhun K., MD	Warm Irradiation and Tocopherol Stabilization of a High-pressure Crystallized UHMWPE for Total Knees	MGH	Minimally Invasive Surgery
2005	Murray, Martha, MD	Enhanced Arthroscopic Repair of Knee Injuries	CHB	Minimally Invasive Surgery
2005	Novak, Vera, MD	Multimodal Pressure Flow (MMPF) Analysis: A Doppler-Based Method to Measure Cerebral Autoregulatory Dynamics	BIDMC	Neurotechnology
2005	Orgill, Dennis, MD	Application of Micro-Mechanical Forces to Accelerate Wound Healing	BWH	Trauma & Casualty Care
2005	Pascual-Leone, Alvaro, MD	DSI-Guided TMS: A System to Improve Focal Precision of Transcranial Brain Stem	BIDMC	Image Guided Therapy
2005	Pigula, Frank A., MD	Fetoscopic Treatment of Congenital Heart Block	CHB	Cardiovascular Disease
2005	Redmond, Robert W., MD	Photochemical Tissue bonding -- A Nanosuture Approach to Vascular Repair	MGH	Minimally Invasive Surgery
2005	Schachter, Steven, MD	Use of a Seizure Detector to Activate the Vagus Nerve Stimulator: Feasibility Study	BIDMC	Neurotechnology
2005	Seiden, Michael, MD	Initiation of a Near-Infrared Imaging Platform in Women with Ovarian Cancer	MGH	Image Guided Therapy
2005	Sundback, Cathryn, MD	Biodegradable Elastomeric Scaffolds for Soft Tissue Engineering	MGH	Tissue Engineering
2005	Thompson, Christopher, MD	Endoscopic Transgastric Surgery of the Lower Abdomen and Pelvis	BWH	Minimally Invasive Surgery
2005	Thompson, Christopher, MD	Per-Oral Endoscopic Gastrojejunal Anastomosis	BWH	Minimally Invasive Surgery
2005	Vacanti, Joseph P., MD	Microvascular Hemofilration: Precursor to a MEMS-based Renal Replacement System	MGH	Tissue Engineering
2005	Van Vliet, Krystyn, PhD	Chemomechanical Profiling of Living Cell Surfaces for Diagnostic Imaging	MIT	Image Guided Therapy
2005	Verrier, Richard, MD	Dynamic Tracking of Cardiac Depolaricationto Estimate Risk of Life-Threatening Arrhythmias	BIDMC	Cardiovascular Disease
2005	Vosburgh, Kirby, PhD	Improved Guidance for Minimally Invasive Surgery	BWH, MGH	Minimally Invasive Surgery
2005	White, Jennifer, MD	Application of Automation and Tissue Engineering to Construct Heart Valves	MGH	Tissue Engineering
2004	Ackerman, Jerome, PhD	MEMS-based Intravascular Devices to Diagnose Cardiovascular Disease	MGH	Tissue Engineering, Cardiovascular Disease
2004	Ackerman, Jerome, PhD	Intravascular MRI Coil Development	MGH	Image Guided Therapy
2004	Borenstein, Jeffrey, PhD	Novel MEMS-based Biodetection System	Draper	Tissue Engineering, Biodetection & Sepsis
2004	Bouma, Brett, PhD	Therapy Enabling Device	MGH	Image Guided Therapy
2004	Bueno, Raphael, MD	BWH OR of the Future	BWH	Clinical Systems Innovation
2004	Colson, Yolonda, PhD	Incorporating Anti-Neoplastic Agents into Surgical Resection Margins	BWH	Minimally Invasive Surgery
2004	Davis, Cristina, PhD	Non-Invasive Breath Analysis	Draper	Biodetection & Sepsis Control
2004	Davis, Cristina, PhD	Bacillus Spore Identification	Draper	Biodetection & Sepsis Control
2004	de Boer, Johannes, PhD	Developing Ultra High Speed OCT	MGH	Image Guided Therapy
2004	Desai, Tejal, PhD	Bioadhesive PMMA Microdevices for Oral Drug Delivery	BU	Biomaterials & Tissue Engineering
2004	Dubowsky, Steven, ScD	Electrostrictive Polymer Artificial Muscle (EPAM) for MRI	MIT	Image Guided Therapy, Biomaterials & Tissue Engineering
2004	Epstein, Laurence, MD	Developing MRI Compatible Devices for MRI and EP Guided Cardiac Ablation	BWH	Image Guided Therapy, Cardiovascular Disease
2004	Gazelle, G. Scott, PhD	OR of the Future Outcomes Project	MGH	Clinical Systems Innovation
2004	Goldman, Julian, MD	Context-Based Smart Physiological Alarm Annunciation	MGH	Clinical Systems Innovation
2004	Guttag, John, PhD	Patient Centric Networking and APplication to Automated Seizure Detection	MIT	Neurotechnology, Clinical Systems Innovation
2004	Guttag, John, PhD	Patient Centric Networking and Robust Patient State Sensing	MIT	Clinical Systems Innovation
2004	Hamblin, Michael, PhD	Macrophage-Targeted Fluorescent Detection and PDT of Vulnerable Atherosclerotic Plaque	MGH	Image Guided Therapy
2004	Isaacson, Keith, MD Sandberg, Warren, PhD	Using RFID Tracking System to Enhance Patient Safety in the OR of the Future	MGH, Newton Wellesley	Clinical Systems Innovation
2004	Jaklitsch, Michael, MD	Mobile Lung Pump to Recover Marginal Donor Lungs	BWH	Trauma & Casualty Care
2004	Jones, Daniel, MD	Liquid Repair of Inguinal Hernia	BIDMC	Minimally Invasive Surgery
2004	Lee, Richard, MD	Developing an Injectable, Self-Assessing Engineered Myocardium	BWH	Biomaterials & Tissue Engineering, Cardiovascular Disease
2004	Orgill, Dennis, PhD	Tension-Induced Angiogenesis in Wound Healing	BWH	Trauma & Casualty Care
2004	Peng, Chung-Kang, PhD	ECG-Based Cardiopulmonary Diagnostics	BIDMC	Cardiovascular Disease
2004	Rogers, Campbell, MD	Anti-Inflammatory and Anti-Proliferative Drug-Eluting Stent Treatment of Vulnerable Plaque Detected by Tomography	BWH	Cardiovascular Disease
2004	Sandberg, Warren, PhD	Clinical Application of Patient-Centric Anesthesia Delivery in OR of the Future	MGH	Clinical Systems Innovation
2004	Scarborough, Donna, MS, PT	Portable Gait Evaluator and Biofeedback Intervention Tool	MGH	Clinical Systems Innovation
2004	Seiden, Michael, PhD	Developing Laparoscopic-Based NIRF Detection System for Molecular Characterization of Intraperitoneal Cancer	MGH	Minimally Invasive Surgery
2004	Sodickson, Daniel, PhD	Microcoils for Electrode-Free Tumor Ablation and Imaging	BIDMC	Image Guided Therapy
2004	Tawakol, Ahmed, MD	Immune Modulation to Enhance Detection and Treatment of Vulnerable Plaques	MGH	Cardiovascular Disease
2004	Tearney, Guillermo, PhD	Low Coherence Interferometry System for Guidance in Lumbar Punctures	MGH	Image Guided Therapy
2004	Tearney, Guillermo, PhD	Polarization Sensitive OCT Assessment of Collagen in Atherosclerotic Plaques	MGH	Image Guided Therapy, Cardiovascular Disease
2004	Vacanti, Joseph, MD	Microvascular Hemofiltration	MGH	Trauma & Casualty Care
2004	Vosburgh, Kirby, PhD	Advanced Ultrasound Visualization of Vasculature for Surgical Guidelines	BWH, MGH	Minimally Invasive Surgery
2004	Westin, Carl-Fredrick, PhD	Image Registration for MRI-Guided Electrophysiological Interventions	BWH	Image Guided Therapy
2004	Young, Conan, PhD	Experimental Approach to Bioengineer Mature Tooth and Jaw Segments	Forsyth	Biomaterials & Tissue Engineering
2004	Yucel, E. Kent, MD	Interactive Platform for MRI-Guided Cardiac Ablation Procedures	BWH	Image Guided Therapy
2003	Bouma, Brett, PhD	Diagnosis of Pancreatic Cysts	MGH	Image Guided Therapy
2003	Bouma, Brett, PhD	Spectrally Encoded Confocal Microscopy	MGH	Image Guided Therapy
2003	Bueno, Raphael, MD	Developing a Gene Ratio-Based Test Kit to Diagnose Lung Cancer	BWH	Biodetection & Sepsis Control
2003	de boer, Johannes, PhD	Diagnosing Osteoarthritis Using Polarization Sensitive OCT	MGH	Image Guided Therapy
2003	Chan, Raymond, PhD	Robust Elastography for IVUS- an OCT-based Imaging of Strain in the Vulnerable Atherosclerotic Plaque	MGH	Image Guided Therapy
2003	Cohen, Richard, PhD	Continuous Cardiac Output for Combat Casualty Care	MIT	Trauma & Casualty Care
2003	Cooper, Jeffrey, PhD	Developing Realistic Simulation-Based Training Systems for Personnel Using the OR Suite	MGH	Simulation
2003	Donaldson, Magruder, MD	Atraumatic Temporary Arterial Branch Perfusion Device	BWH	Trauma & Casualty Care
2003	Dubowsky, Steven, PhD	Electrostrictive Polymer Artificial Muscle (EPAM) Devices for Magnetic Resonance Imaging	MIT	Image Guided Therapy, Biomaterials & Tissue Engineering
2003	Ellsmere, James, MD	Image-Guided Endoscopy for LAPUS Project	BWH	Minimally Invasive Surgery, Image Guided Therapy
2003	Ferrigno, Massimo, MD	Field Cooling of Injured Soldiers	BWH	Trauma & Casualty Care
2003	Frangioni, John, PhD	Functional intraoperative Imaging for Cardiac Surgery and Gene Therapy	BIDMC	Image Guided Therapy
2003	Gazelle, G. Scott, PhD	OR of the Future Outcomes	MGH	Clinical Systems Innovation
2003	Gazelle, G. Scott, PhD	Vulnerable Plaque Outcomes	MGH	Cardiovascular Disease
2003	Gold, Herman, MD	Percutaneous Myocyte Replacement for CHF	MGH	Biomaterials & Tissue Engineering
2003	Grant, Aaron, PhD	Radio Frequency Impedance Mapping for Medical Imaging	BIDMC	Image Guided Therapy
2003	Greenman, Robert, PhD	MRI of Carotid Plaques at 3 Tesla	BIDMC	Image Guided Therapy
2003	Guttag, John, PhD	Patient-Centric Networking and Applications	MIT	Clinical Systems Innovation
2003	Hamblin, Michael, PhD	Macrophage-Targeted Photodynamic Detection and Therapy of Vulnerable Plaque	MGH	Image Guided Therapy, Cardiovascular Disease
2003	Hirsh, Joshua, MD	Use of Radio Frequency Ablation to Treat Metastatic Disease of the Spine	BIDMC	Minimally Invasive Surgery
2003	Hynynen, Kullervo, PhD	Noninvasive Image-Guided Opening of the Blood-Brain Barrier	BWH	Image Guided Therapy, Minimally Invasive Surgery
2003	Isaacson, Keith, MD	Measuring Impact of a Passive Wireless Tracking System	MGH, Newton Wellesley	Clinical Systems Innovation
2003	Jaklitsch, Michael, MD	Prostate Cancer	BWH	New Initiatives
2003	Kaebling, Leslie, PhD David Rattner, MD	Learning Predictive Rules from Medical Data	MIT, MGH	Clinical Systems Innovation
2003	Khan-Butler, Saad, MD	Continuous Cerebral Imaging in the ICU	MGH	Image Guided Therapy
2003	Levine, Robert, PhD	Active Patch Therapy for Ischemic Mitral Regurgitation	MGH	Minimally Invasive Surgery
2003	McDougall, W. Scott, MD	A Method and Device for Bladder Mapping	MGH	New Initiatives
2003	Mezrich, Reuben, PhD	Optically Controlled Neural Prosthesis	BWH, MIT	Neurotechnology
2003	Mihaljevic, Tomislav, MD	Real-Time Intraoperative Functional Imaging of Myocardial Injury and Graft Patency	BWH	Image Guided Therapy
2003	Pascual-Leone, Alvaro, PhD	System to Target Brain Areas for Transcranial Magnetic Stimulation in Stroke	BIDMC	Neurotechnology
2003	Redmond, Robert, PhD	Photochemical Tissue Bonding	MGH	Biomaterials & Tissue Engineering
2003	Shortkroff, Sonya, PhD	Nanofibrous Scaffolds for Cartilage Regeneration	BWH	Biomaterials & Tissue Engineering
2003	Slocum, Alexander, PhD	External Mitral Annuloplasty	MIT	Minimally Invasive Surgery
2003	Srinivasan, Mandayan, PhD	High-Frequency Ultrasound Imaging and Characterization of Skin Lesions in vivo	MIT	Image Guided Therapy
2003	Tawakol, Ahmed, MD	In vivo Detection of Inflamed Plaques	MGH	Cardiovascular Disease
2003	Tearney, Guillermo, PhD	Speckle-Imaging for Plaque Characterization	MGH	Image Guided Therapy, Cardiovascular Disease
2003	Torchiana, David, MD	Chest Tube Access	MGH	Minimally Invasive Surgery
2003	Troulis, Maria, DDS	Minimally Invasive Reconstruction of Midfacial Skeleton	MGH	Minimally Invasive Surgery
2003	Vacanti, Joseph, MD	Tissue Engineering Program	MGH	Biomaterials & Tissue Engineering
2003	Zapata, Angela, PhD	Detection of Pentane in Patient Exhaled Breath by FAIMS	Draper	Biodetection & Sepsis Control
2003	Zapata, Angela, PhD	Characterization of a Pyrolysis-Planar FAIMS for the Detection of Bacillus Spores	Draper	Biodetection & Sepsis Control
2002	Oesterle, Stephen, MD	Endovascular Devices Core Lab	MGH	Minimally Invasive Surgery
2002	Oesterle, Stephen, MD Craig Thompson, MD	Cardiomyocyte Repopulation	MGH	Cardiovascular Disease
2002	Oesterle, Stephen, MD Jerome Ackerman, PhD	Magnetic Resonance Compatible Devices	MGH	Image Guided Therapy
2002	Stevenson, William, MD	Radio Frequency Ablation with Needle-Tipped Catheter	BWH	Minimally Invasive Surgery
2002	Oesterle, Stephen, MD	Atrial Fibrillation Ablation with MR Guidance	MGH	Image Guided Therapy
2002	Rattner, David, MD Keith Isaacson, D	Blake OR-Advanced Procedure Room and Innovation Laboratory	MGH	Minimally Invasive Surgery, Clinical Systems Innovation
2002	Torchiana, David, MD	Robotics in Cardiac Surgery	MGH	Cardiovascular Disease
2002	Gazelle, G. Scott, MD; Stahl,James, MD	Minimally Invasive Surgery Outcomes	MGH	Minimally Invasive Surgery
2002	Whattaker, David, MD; Rattner, David, MD	Gallbladder Extractor Device	MGH	Minimally invasive Surgery
2002	Sims, Nathaniel, MD	Indoor Tracking Location System Development	MGH	Clinical Systems Innovation
2002	Wee, Jon, MD	Off-Pump CABG Myocardial Protection	BWH	Minimally Invasive Surgery
2002	Sims, Nathaniel, MD John Guttag, PhD	Patient Monitoring and Communications	MGH, MIT	Clinical Systems Innovation
2002	Cohn, Lawrence, MD	Focused Ultrasound with Albumin-Coated Microbubbles	BWH	Image Guided Therapy
2002	Lim, Keng R. Rox Anderson, MD	Microsurgical Laser Scalpel Based on Spectroscopic Feedback: The "Smart Scalpel"	MGH	Image Guided Therapy, Minimally Invasive Surgery
2002	Slocum, Alexander, PhD	Breast immobilization for MR_Guided Needle Biopsy	MIT	Minimally Invasive Surgery
2002	Slocum, Alexander, PhD	Material Handling by Magnetic Wheel Overhead Transport System	MIT	Clinical Systems Innovation
2002	Bouma, Brett. E., PhD	Cellular Resolution Endoscope and Catheter-Based Optical Imaging	MGH	Image Guided Therapy
2002	Hynynen, Kullervo, PhD	Non-Invasive Image-Guided Opening of the Blood-Brain Barrier	BWH	Image Guided Therapy
2002	Westin, Carl-Fredrick, PhD	Automated Segmentation of Anatomy from CT and MRI	BWH	Image Guided Therapy
2002	Langer, Robert, ScD	Degradable Conductive polymers	MIT	Biomaterials & Tissue Engineering
2002	MacLaughlin, David, PhD	Mullieran Inhibiting Substance (MIS) for Ovarian Cancer	MGH	Biomaterials & Tissue Engineering
2002	Vacanti, Joseph, MD	Tissue Engineering: Vascular Systems and Angiogenesis	MGH	Biomaterials & Tissue Engineering
2002	Vacanti, Joseph, MD	Tissue Engineering: 3D Tissue Design	MGH	Biomaterials & Tissue Engineering
2002	Vacanti, Joseph, MD; Borenstein, Jeffrey, PhD	Tissue Engineering Vascularized Tissue in vitro for Implant	MGH, Draper	Biomaterials & Tissue Engineering
2002	Young, Conan, PhD	Experimental Biological Tooth Replacement	Forsyth	Biomaterials & Tissue Engineering
2002	Dawson, Steven, MD	Enabling Technologies for Medical Simulation	MGH	Simulation
2002	Dube, Christopher, PhD	Real-Time Blood Assay	Draper	Trauma & Casualty Care
2002	Puyana, Juan Carlos, MD; Asada, Harry, PhD	Endpoints of Cellular Resuscitation in Hemorrhagic Shock	MIT, UPITT	Trauma & Casualty Care
2002	Zapata, Angela, PhD	Development and Characterization of Pyrolysis: FAIMS Analyzer for the Detection of Bacillus Spores	Draper	Trauma & Casualty Care
2002	Larson, Kent	An Integrated Approach to "Healing Environments"	MIT	Trauma & Casualty Care
2002	Scarborough, Donna, PhD	Gait Evaluation	MGH	Trauma & Casualty Care
2002	Ling, Geoffrey, MD, PhD	RAFTS/Biglove	USUHS	Trauma & Casualty Care
2002	Wiesmann, William, MD	Parallel Computer Processing and Modeling Use in Medical Monitoring	Harvey Mudd	Trauma & Casualty Care
2002	Muller, James, MD; Brady, Thomas, MD	Vulnerable Plaque Program	MGH	Cardiovascular Disease
2002	Brady, Thomas, MD; Bouma, Brett, PhD	Characterization of Vulnerable Plaque	MGH	Cardiovascular Disease
2002	Fischman, Alan, MD	Detection of Vulnerable Atherosclerotic Plaques with Radionuclide Technology	MGH	Cardiovascular Disease
2002	Gazelle, G. Scott, MD, PhD	Vulnerable Plaque Program Outcomes	MGH	Cardiovascular Disease
2002	Boas, David, PhD	Continuous Monitoring of Stroke Using Diffuse Optical Tomography	MGH	Image Guided Therapy
2002	Schwamm, Lee, MD	Tele-Stroke	MGH	Clinical Systems Innovation
2002	Gonzalez, R. Gilberto, MD, PhD	MGH XMR Suite	MGH	Image Guided Therapy
2002	Borsook, David, MD, PhD	Optical Imaging for Rapid Determination of Pain: Correlation with fMRI	MGH	Image Guided Therapy
2002	Langer, Robert, ScD	Degradable conductive polymers	MIT	Biomaterials/Tissue Repair
2002	MacLaughlin, David, PhD	Mullerian Inhibiting Substance (MIS) for ovarian cancer	MGH	Biomaterials/Tissue Repair
2002	Vacanti, Joseph, MD	Tissue engineering: vascular systems and angiogenesis	MGH	Biomaterials/Tissue Repair
2002	Vacanti, Joseph, MD	Tissue engineering: 3D tissue design	MGH	Biomaterials/Tissue Repair
2002	Vacanti, Joseph, MD; Borenstein, Jeffrey, PhD	Tissue engineering vascularized tissue in vitro for implant	MGH & Draper	Biomaterials/Tissue Repair
2002	Young, Conan, PhD	Experimental biological tooth replacement	Forsyth Institute	Biomaterials/Tissue Repair
2002	Bouma, Brett E., PhD	Cellular resolution endoscope and catheter-based optical imaging	MGH	Image Guided Technology
2002	Hynynen, Kullervo, PhD	Non-invasive image guided opening of the blood-brain barrier	BWH	Image Guided Technology
2002	Westin, Carl-Fredrik, PhD	Automated segmentation of anatomy from CT and MRI	BWH	Image Guided Technology
2002	Slocum, Alexander, PhD	Breast immobilization for MR-guided needle biopsy	MIT	MIS
2002	David Rattner, MD Isaacson, Keith, MD	Blake OR-Advanced Procedure Room and Innovation Laboratory, APRIL	MGH	MIS
2002	Torchiana, David, MD	Robotics in cardiac surgery	MGH	MIS
2002	Gazelle, G. Scott, MD, PhD; Stahl, James, MD	Minimally Invasive Surgery outcomes	MGH	MIS
2002	Whittaker, David, MD; Rattner, David, MD	Gallbladder extractor device	MGH	MIS
2002	Sims, Nathaniel, MD	Indoor tracking location system development	MGH	MIS
2002	Wee, Jon, MD	Off-pump CABG myocardial protection	BWH	MIS
2002	Sims, Nathaniel, MD; Guttag, John, PhD	Patient monitoring and communications	MGH & MIT	MIS
2002	Cohn, Lawrence, MD	Focused ultrasound with albumin-coated microbubbles	BWH	MIS
2002	Lim, Keng R. Rox Anderson, MD	Microsurgical laser scalpel based on spectroscopic feedback: the "Smart Scalpel"	MGH	MIS
2002	Slocum, Alexander, PhD	Material Handling by Magnetic Wheel Overhead Transport System	MIT	MIS
2002	Oesterle, Stephen, MD	Endovascular devices core lab	MGH	Endovascular Devices
2002	Oesterle, Stephen, MD; Thompson, Craig, MD	Cardiomyocyte repopulation	MGH	Endovascular Devices
2002	Oesterle, Stephen, MD; Ackerman, Jerome, PhD	Magnetic resonance compatible devices	MGH	Endovascular Devices
2002	Stevenson, William, MD	Radio frequency ablation with needle-tipped catheter	BWH	Endovascular Devices
2002	Oesterle, Stephen, MD	Atrial fibrillation ablation with MR guidance	MGH	Endovascular Devices
2001	Slocum, Alexander, PhD	Precisely aligned transducers (PAT) for breast health monitoring	MIT	New Initiatives
2001	Adams, David, MD	MI pulmonary artery binding of porcine cardiac xenographs	BWH	New Initiatives
2001	Stone, Peter, MD	Detecting endothelial sheer stress: intravascular flow profiling	BWH	New Initiatives
2001	Krane, Robert, MD; Hunter, Ian, PhD	Incontinence device using novel conductive polymer	MGH & MIT	New Initiatives
2001	Pratt, Gil, PhD	A magnetic enteroscope	MIT	New Initiatives
2001	Nishioka, Norman, MD	Multispectral imaging for endoscopy and laparoscopy	MGH	New Initiatives
2001	Perlman, Lev, MD	Elastically scattered polarized light	BIDMC	New Initiatives
2001	Boas, David, PhD	Continuous monitoring stroke: diffuse optical tomography	MGH	Stroke
2001	Gonzalez, R. Gilberto, MD, PhD	Stroke patient transport	MGH	Stroke
2001	Muller, James, MD	Vulnerable plaque program	MGH	Vulnerable Plaque
2001	Hamblin, Michael, PhD	Treatment of vulnerable atherosclerotic plaques with macrophage-targeted photodynamic therapy	MGH	Vulnerable Plaque
2001	Brady, Thomas, MD	CT and MRI imaging of vulnerable plaque	MGH	Vulnerable Plaque
2001	Vermani, Renu, MD	Vulnerable plaque	Armed Forces Institute of Pathology (AFIP)	Vulnerable Plaque
2001	Furie, Karen, MD	OCT imaging of carotid plaques	MGH	Vulnerable Plaque
2001	Dubé, Christopher, PhD	Real-time blood assay	Draper	Trauma/Critical Care
2001	Puyana, Juan Carlos, MD	NIR of tissue pH & O2 in ischemia	BWH	Trauma/Critical Care
2001	Wiesmann, William, MD	Internet system: home-based health monitoring	Harvey Mudd College	Trauma/Critical Care
2001	Langer, Robert, ScD	Polymer-Based Gene Delivery Platform	MIT	Biomaterials/Tissue Repair
2000	Langer, Robert, ScD	Degradable conductive polymers	MIT	Biomaterials/Tissue Repair
2001	Vacanti, Joseph, MD; Borenstein, Jeffrey, PhD	Engineered vascularized tissue in-vitro for implant	MGH & Draper	Biomaterials/Tissue Repair
2001	Vacanti, Joseph, MD	Engineered vascularized tissue in vitro for implant	MGH	Biomaterials/Tissue Repair
2001	Jolesz, Ferenc, MD	Focused ultrasound treatment for breast cancer	BWH	Image Guided Technology
2001	Westin, Carl-Fredrik, PhD	Segmentation of bone from CT & vessels from MRA	BWH	Image Guided Technology
2001	Warfield, Simon, MD	Intraoperative MRI-liver cryotherapy testbed: ORF	BWH	Image Guided Technology
2001	Howe, Robert, PhD	Registered ultrasound for surgical guidance	HMA	Image Guided Technology
2001	Jolesz, Ferenc, MD	Image-guided endoscopy	BWH	Image Guided Technology
2001	Kaban, Leonard, DDM, MD	3-D image planning system: endoscopically placed distraction device	MGH	MIS
2001	Torchiana, David, MD	Robot-assisted coronary bypass surgery	MGH	MIS
2001	Acker, David, MD	Endoscopic laser surgery for severe twin-twin transfusion syndrome	BWH	MIS
2001	Gaissert, Henning, MD	Thorascopic and laparoscopic esophagectomy	BWH	MIS
2001	Aklog, Lishan, MD	Intraluminal coronary shunts versus extraluminal occlusion	BWH	MIS
2001	Rattner, David, MD	OR of the future	MGH	MIS
2001	Yucel, E. Kent, MD	Intravascular MR imaging wire	BWH	Catheter-Based Intervention
2000	Bosch, Johanna, PhD	Outcome assessment in menorrhagia	MGH	New Initiatives
2000	Peterson, John, PhD	Develop fiberguides for laser-pulsed fluid wave for vasodilation	MGH	New Initiatives
2000	Sorensen, Gregory, MD	Assessment of neuroprotection	MGH	Stroke
2000	Schwamm, Lee, MD	Remote stroke video-conferencing project (RSVP)	MGH	Stroke
2000	Bouma, Brett, PhD	Detection of vulnerable plaques: OCT	MGH	Vulnerable Plaque
2000	Jang, Ik-Kyung, MD	Coronary angioscopy to detect vulnerable plaques	MGH	Vulnerable Plaque
2000	Reddy, Vivek, MD	Catheter-based ablation VT/VF using substrate mapping	MGH	Vulnerable Plaque
2000	Ling, Geoffrey S., MD, PhD	Multi RF diagnostic tool: trauma casualty care mgt	USUHS	Trauma/Critical Care
2000	Cunningham, Brian, PhD	Real-time blood assay	Draper	Trauma/Critical Care
2000	Wiesmann, William, MD	Internet system: home-based health monitoring	Harvey Mudd College	Trauma/Critical Care
2000	Dawson, Steven, MD	Enabling technologies for med simulation	MGH	Medical Simulation
2000	Langer, Robert, ScD	Degradable conductive polymers	MIT	Biomaterials/Tissue Repair
2000	MacLaughlin, David, PhD	In vivo recombinant protein delivery device	MGH	Biomaterials/Tissue Repair
2000	Vacanti, Joseph, MD	Engineered vascularized tissue in-vitro for implant	MGH	Biomaterials/Tissue Repair
2000	Vacanti, Joseph, MD; Borenstein, Jeffrey, PhD	Engineered vascularized tissue in-vitro for implant	MGH & Draper	Biomaterials/Tissue Repair
2000	Gill, Thomas, MD, MGH	Minimally-invasive meniscal repair: tissue engineering cartilage	MGH	Biomaterials/Tissue Repair
2000	Adzick, Scott, MD	Fetal Tissue Engineering	Childrens Hospital of Philadelphia	Biomaterials/Tissue Repair
2000	Talora, Claudio, MS	Skin as a source of multipoint stem cells	MGH	Biomaterials/Tissue Repair
2000	Nishioka, Norman, MD	Endoscopic optical coherence tomography-OCT	MGH	Image Guided Technology
2000	Kosofsky, Barry, MD, PhD	OCT of newborns as risk	MGH	Image Guided Technology
2000	Hunter, Ian, PhD	Develop servo-controlled microsurgical laser scalpel	MIT	MIS
2000	Aklog, Lishan, MD	Endoscopic computer enhanced cardiac surgery (DaVinci)	BWH	MIS
2000	Torchiana, David, MD	Application of robotics interface in surgery	MGH	MIS
2000	Rattner, David, MD	OR of the future	MGH	MIS
2000	Howe, Robert, PhD	Virtual fixtures robot assist MI cardiac surgery	HMA	MIS
2000	Stojanovic, Milan, MD	Spine treatment for discogenic low back pain	MGH	MIS
2000	Oesterle, Stephen, MD	Cardiomyocyte repopulation: percutaneous delivery	MGH	Catheter-Based Intervention
1999	Kerrigan, Casey, MD	Improved tactile sensation for management of sensory deficits with stroke	SRH	New Initiatives
1999	Weaver, James, PhD	Transdermal drug delivery - skin electrophoresis	MIT	New Initiatives
1999	Sorensen, Gregory, MD	Assessment of neuroprotection	MGH	Stroke
1999	Lee, Albert, MD	Tissue characteristics in human acute ischemic stroke	MGH	Stroke
1999	Gonzalez, R. Gilberto, MD, PhD	Laser thrombolysis of clot	MGH	Stroke
1999	Brisman, Jonathan, MD	Use of proton beam radiation for intractable epilepsy	MGH	Stroke
1999	Greenberg, Steven, MD	Measure CV reactivity - functional MRI	MGH	Stroke
1999	Boas, David, PhD	Continuous monitoring stroke: diffuse optical tomography	MGH	Stroke
1999	Bouma, Brett, PhD	Detection of vulnerable plaques: OCT	MGH	Vulnerable Plaque
1999	Madsen, Joren, MD	Preventing embolic brain injury	MGH	Vulnerable Plaque
1999	Puyana, Juan Carlos, MD	NIR of tissue pH & O2 in ischemia	MGH	Trauma/Critical Care
1999	Ling, Geoffrey S., MD, PhD	Multi RF diagnostic tool: trauma casualty care mgt	USUHS	Trauma/Critical Care
1999	Cunningham, Brian, PhD; Dubé, Christopher, PhD	Real-time blood assay	Draper	Trauma/Critical Care
1999	Wiesmann, William, MD	Internet system: home-based health monitoring	Harvey Mudd College	Trauma/Critical Care
1999	Dawson, Steven, MD Mukund Desai, PhD	Medical Simulation	MGH & MIT	Medical Simulation
1999	Dawson, Steven, MD; Salisbury, Kenneth, PhD	Enabling technology for medical simulation	MGH & MIT	Medical Simulation
1999	Vacanti, Joseph, MD; Borenstein, Jeffrey, PhD	Engineering vascularized tissue in vitro for implant	MGH & Draper	Biomaterials/Tissue Repair
1999	Vacanti, Joseph, MD	Engineering vascularized tissue in-vitro for implant	MGH	Biomaterials/Tissue Repair
1999	Langer, Robert, ScD	Poly nanoparticles: local high energy gene transfer	MIT	Biomaterials/Tissue Repair
1999	Murray, Martha, MD	Develop tissue scaffold - intra articular use	MGH	Biomaterials/Tissue Repair
1999	Westin, Carl-Fredrik, PhD	Segmentation of bone from CT & vessels from MRA	BWH	Image Guided Technology
1999	Nishioka, Norman, MD	Endoscopic optical coherence tomography-OCT	MGH	Image Guided Technology
1999	Nishioka, Norman, MD	Endoscopic imaging of fluorescence in the esophagus - ALA detection of dysplasia	MGH	Image Guided Technology
1999	Jolesz, Ferenc, MD	Focused ultrasound-Tx breast cancer	BWH	Image Guided Technology
1999	Grimson, Eric, PhD	Real-time registration of intra-op ultrasound with pre-op CT/MR for image guided therapy	MIT	Image Guided Technology
1999	Rattner, David, MD	OR of the future	MGH	MIS
1999	Kaban, Leonard, DDM, MD	3-D image guided planning: endoscopically placed distraction device	MGH	MIS
1999	Ingenito, Edward, MD, PhD	Lung volume reduction	BWH	MIS
1999	Torchiana, David, MD	Robot-assisted coronary bypass surgery	MGH	MIS
1999	Gimbrone, Michael, MD	Endothelial activation markers - Cardiovascular Disease (CVD)	BWH	MIS
1999	Rattner, David, MD	Indocyanine green for subsurface vessels	MGH	MIS
1998	Anderson, R. Rox, MD	Endoscopic reversible laryngeal closure to prevent chronic aspiration	MGH	New Initiatives
1998	Weissleder, Ralph, MD	Near infrared fluorescence (NIRF) imaging with novel activatable probes	MGH	New Initiatives
1998	Stafford, Randall, MD, PhD	Patterns of technology adoption: laparoscopic cholecystectomy use in Eastern Massachusetts	MGH	New Initiatives
1998	LaMuraglia, Glenn, MD	Photodynamic therapy for the inhibition of arterial restenosis	MGH	New Initiatives
1998	Tanabe, Kenneth, MD	RF energy induced hyperthermia of liver tumors combined with hepatic arterial delivery of melphalan	MGH	New Initiatives
1998	Rogers, Campbell, MD	Smart catheters: transforming the transluminal balloon catheter into a remote microsensor	MIT	New Initiatives
1998	Yaremchuk, Michael, MD	Tissue engineered cartilage for minimally invasive implantation	MGH	New Initiatives
1998	Keane, David, MD	Catheter ablation of atrial fibrillation under guidance of intra-cardiac echocardiography	MGH	New Initiatives
1998	Moharir, Vik, MD	Computer assisted 3D reconstruction of head and neck tumors using merged CT and MR images	BWH	New Initiatives
1998	Paithankar, Dilip, PhD	Detection of sub-surface blood vessels during GI endoscopy	MGH	New Initiatives
1998	Basdogan, Cagatay, PhD	Force-reflecting models for simulating laparoscopic surgical procedures in virtual reality systems	MIT	New Initiatives
1998	Timmons, Michael, BS	Fusion of medical imaging data of the sterile operating field during intracranial surgery	MIT	New Initiatives
1998	Marecos, Edgardo, MD	In vivo mapping of brain/tumor interface with a molecular probe	MGH	New Initiatives
1998	Islam, Sallem, MD	Intratracheal pulmonary ventilation: a novel method for neonatal ventilation	MGH	New Initiatives
1998	Mycek, Mary Ann, PhD	Tissue characterization via endoscopic image analysis	MGH	New Initiatives
1998	Anderson, R. Rox, MD	Vasodilatation using laser-induced pulse fluid wave	MGH	New Initiatives
1998	Leykin, Lucy, PhD	A study of the non-invasive laser system for intracytoplasmic sperm injection	MGH	New Initiatives
1998	Bogdanov, Alex, PhD	Clinical trial of a soluble drug carrier for tumor therapy	MGH	New Initiatives
1998	Ortel, Bernhardt, MD	Construction and evaluation of an in vivo hemocytometer	MGH	New Initiatives
1998	Torchiana, David, MD	Effects of a novel tissue sealant applied to the anastomosis of coronary bypass procedure in dogs	MGH	New Initiatives
1998	Duska, Linda, MD	Fluorescence detection and laser treatment of female lower genital tract dysplasia utilizing 5-aminolevulinic acid(ALA)-induced protoporphyrin IX	MGH	New Initiatives

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regarding Commercialization Opportunities.