CIMIT Program: Minimally Invasive Surgery

Minimally Invasive Surgery (MIS)

MAKING SURGERY SAFER, AND RECOVERY FASTER
AND LESS PAINFUL FOR PATIENTS

Minimally Invasive Surgery (MIS) decreases risk and shortens post-surgical recovery time. Improved minimally invasive techniques, like laparoscopic surgery, are most effective when the tools are flexible, sophisticated, and incorporate advanced imaging techniques.

New devices, better optics and creative multimodal approaches to disease management have set the stage for the next phase of less invasive surgical therapy.

CIMIT’s Minimally Invasive Surgery progam is focused on making surgery safer and more precise, exploring the next generation of less invasive surgical therapy. Recent projects involve developing tools and procedures for Natural Orifice Translumenal Endoscopic Surgery (NOTES), which could make surgery completely free of incisions, while reducing pain and disability. Through the NOTES initiative, complex surgeries could eventually become outpatient procedures.

» VIDEO: What is the Boston-based NOTES Initiative?

RECENT NEWS:

12.3.09
Medical News Today: World First: Rectal Tumor Removed Through Anus, Avoiding Painful Abdominal Incisions

VIDEO: Transanal Endoscopic Microsurgery (TEM)

Additional Coverage on TEM Surgery: EndoNurse, EurekAlert!, LittleAbout, blog.taragana.com, Procto-Med.com, HealthCareTips.org

6.22.09
wbur.org: You Want To Take My What Out Of My Where? Hospitals Experiment With Orifice Surgery

Projects
Publications
Forum/Events
In The News

FY 2010 - 2008 Minimally Invasive Surgery Projects
YEAR	PRINCIPAL INVESTIGATOR	INSTITUTION	PROJECT TITLE
2010 - 2008	David Rattner, MD, and Chris Thompson, MD, MSc	Massachusetts General Hospital & Brigham and Women’s Hospital	Strategic Project on Natural Orifice Translumenal Endoscopic Surgery
2008	Peter Masiakos, MD	Massachusetts General Hospital	Development of an Endoscopic Fiberoptic Device and Biodegradable Scaffolds for Minimally Invasive Closure of Tracheosophageal Fistulas and Patent Foramina
2008	Nathan McDannold, PhD	Brigham and Women’s Hospital	Herceptin delivery to breast cancer metastases in the central nervous system via focused ultrasound-induced blood-brain barrier disruption
2008	Marvin Ryou	Brigham and Women’s Hospital	Systematic Mapping of NOTES Access Sites in Human Cadavers
2008	Marvin Ryou	Brigham and Women’s Hospital	Magnetic Retraction for Advanced NOTES Procedures

» View all CIMIT-Funded Projects. Contact Haleh Armian, CIMIT Senior Manager, Business Development for more information regarding Commercialization Opportunities.

Recent Publications by CIMIT Investigators
INVESTIGATOR/AUTHOR	PUBLICATION	ARTICLE	DATE
Willingham, F. F., Gee, D.W., Lauwers, G., Brugge, W. R., Rattner, D. W.	Surg Endosc. (2008) 22:2117-2122	Natural Orifice Transesophageal Mediastinoscopy and Thoracoscopy	2008
Alam, H. B., Shults, C., Ahuja, N., Ayuste, E. C., Chen, H., Koustova, E., Sailhamer, E. A., Li, Y., Liu, B., de Moya, M., Velmahos, G. C.	Resuscitation Sep 4, 2007	Impact of Resuscitation Strategies on the Acetylation Status of Cardiac Histones in a Swine Model of Hemorrhage	2007
Sailhamer, E. A., Chen, Z., Ahuja, N., Velmahos, G. C., de Moya, M., Rhee, P., Shults, C., Alam, H. B.	J Am Coll Surg 204(4):642-53	Profound Hypothermic Cardiopulmonary Bypass Facilitates Survival without a High Complication Rate in a Swine Model of Complex Vascular, Splenic, and Colon Injuries	2007
Velmahos, G. C., Spaniolas, K., Duggan, M., Alam, H. B., Tabbara, M., de Moya, M., Vosburgh, K.	J Trauma 63(2):285-8, discussion 288-90	Abdomainal Insufflation for Control of Bleeding After Severe Splenic Injury	2007
Stahl, J.E., Goldman, J.M., Rattner, D.W., Gazelle, G.S.	J. Surg Res.	Related Articles, Links Adapting to a New System of Surgical Technologies and Perioperative Processes Among Clinicians	2007 Jan. 31 (Epub ahead of print)
Ryou, M., Rattner, D., Pai, R., Thompson, C.	Surg Endosc. 12:677-80	Evaluating an Optimal Gastric Closure Method for Trans-Gastric Surgery	2007
Pai, R., Fong, D.G., Bundga, M.E., Odze, R.D., Rattner, D.W., Thompson, C.C.	Gastrointestinal Endoscopy 64:428-34	Transcolonic endoscopic cholesystectomy: a NOTES survival study in a porcine model.	2006
Rattner, D.W.	Surg Endosc 20:1802-8	Innovation, Disruption and the perils of success.	2006
Rattner, D.W., Kalloo, A.	Surg Endosc. 20:329-33	The ASGE/SAGES Working group on Natural Orifice Transluminal Endoscopic Surgery WHITE PAPER	2006

Minimally Invasive Surgery at the CIMIT Forum and Past Events
EVENT	DATE	SPEAKERS	DETAIL
Forum: Minimally Invasive Surgery	May 27, 2008	Ali Tavakkolizadeh, MB, BS: Harvard Medical School Dennis Fowler, MD: NewYork-Presbyterian Hospital	• Minimally Invasive Surgery for GI Cancer • Single Port Laparoscopy or NOTES: A Form of Image Guided Therapy?
Forum: Current Therapies for BPH and the Search for Smart Engineering Solutions	Feb. 12, 2008	Shahin Tabatabaei, MD: MGH Kevin Loughlin , MD: BWH Michael Callum, MD: North Shore Medical Center	• Laser BPH Therapy • BPH Medical Therapy
Forum: Challenges and Opportunities in Office-Based Medicine	Oct. 9, 2007	Keith Isaacson, MD; HMS, BWH, BWH Fred Shapiro, DO; HMS, BIDMC Beverly Philip, MD; HMS, BWH Lisa Warren, MD; MGH	• Office-based Gynecologic Procedures • Office-based Anesthesia • Technology Implications of Office-based Anesthesia Safety • Regional Anesthesia in the Office Based Setting

Minimally Invasive Surgery News
ARTICLE TITLE	PUBLICATION	DATE
World First: Rectal Tumor Removed Through Anus, Avoiding Painful Abdominal Incisions	Medical News Today	Dec. 3, 2009
You Want To Take My What Out Of My Where? Hospitals Experiment With Orifice Surgery	wbur.org	June. 22, 2009
A New Way to Perform Surgery	KTVU Channel 2	Jul. 15, 2008
Surgery Revolution	Philadelphia Bulletin	May 15, 2008
Open Wide. No, Wider. Are we ready for an era of 'natural-orifice surgery'?	Newsweek	Apr. 14, 2008
Scar-Free Surgery: In New Operation, Doctors Insert Tools Through Natural Orifices, Keeping Skin Intact	Boston Globe	Jan. 7, 2008
Novel NOTES Causes Docs to Rethink Incision Decision	Boston Business Journal	Jul. 13, 2007
Hype, Theories on NOTES Abound, But Where It Is All Headed Is Anyone’s Bet (PDF)	Gastroenterology & Endoscopy News	Jul. 2007
A New Step in Scarless Surgery	Proto	Summer 2007

Video: CIMIT Life-Saving Innovation in Early Stage of Trauma.

Program Leader
David Rattner, MD

CIMIT RESPONSIBILITIES
Program Leader,
Minimally Invasive Surgery

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